Faculty Research Initiatives — Clinical Trials
Innovations in diagnostic and interventional imaging stem from research. In clinical trials, our faculty bridges ideas to advancements in medical therapies.
The VCU Department of Radiology research portfolio extends from basic research to clinical trials. Radiology faculty members conduct research in a wide variety of clinical areas, including cancer treatment and diagnosis, cardiovascular disease, women’s health, trauma and obesity.
Current projects include:
- A five-year National Institutes of Health (NIH) basic research grant for the development of metallic nanoparticles.
- A NIH grant for a phase one clinical trial of a new imaging agent for identification of tumor resistance.
The phase one clinical trial demonstrates our comprehensive approach and commitment to bringing new discoveries into clinical use. Specifically, the imaging agent was developed by a VCU faculty member during a fellowship at NIH, scientists at VCU developed an automated method to produce the agent and a VCU Massey Comprehensive Cancer Center grant funded the first in-human pilot study.
PROTOCOL NO.: DENALI
Principal Investigator: Daniel J. Komorowski, M.D.
Title: A Prospective, Multi-Center, Study of the BARD® DENALI® Retrievable Vena Cava Filter System
Sponsor: BARD Peripheral Vascular, Inc.
Imaging/Procedure: Interventional Radiology Filter Placement
Status: In Maintenance
PROTOCOL NO.: EDCCTA-0601
Principal Investigators: John D. Grizzard, M.D., and Michael C. Kontos, M.D. (Cardiology)
Title: Utility of 64-slice Multidetector CT Coronary Angiography in the Evaluation of Low- and Intermediate-risk Chest Pain Patients
Disease State: Chest pain, acute coronary syndromes
Drug/Agent: Isovue-370™
Imaging/Procedure: Coronary CT Angiography
Status: Closed
PROTOCOL NO.: RG1068-15-02
Principal Investigator: Ann S. Fulcher, M.D., FACR
Title: A Phase II Study to Assess the Safety and Methods for Determining the Efficacy of RG1068 (Synthetic Human Secretin): Enhanced Magnetic Resonance Cholangiopancreatography in the Evaluation of Patients with a History of Pancreatic Abnormalities
Sponsor: Repligen
Location: National, multi-center
Drug/Agent: RG1068 (Synthetic Human Secretin)
Imaging/Procedure: Magnetic Resonance Cholangiopancreatography
Status: Closed